FRAXA President & Co-Founder Katie Clapp on Diane Rehm Show

On Tuesday, 3/19, The Diane Rehm Show, a syndicated radio show, will discuss choosing efficient and effective charities with author Ken Stern and guests including Katie, during the 11am-noon hour. http://thedianerehmshow.org/shows/2013-03-19/choosing-efficient-and-effective-charities

CTEP now available! Attention all neuroscientists!

I get a lot of inquiries from scientists asking about the availability of CTEP, the latest and greatest mGluR5 antagonist. It’s much more potent and much longer acting than MPEP or fenobam, and is comparable to Roche’s lead mGluR5 antagonist currently in clinical trials for fragile X—not surprising, since CTEP was developed by Roche scientists. ...

2 New Arbaclofen Studies Getting Lots of Press!

Two complementary studies were just published in Science Translational Medicine, and they’ve been getting a ton of attention in the media. Since lots of people are asking about these articles, and reporters have been calling to get my comments (and occasionally misquoting me), I thought I’d give my official commentary here. The first article (Henderson ...

What works, and what doesn’t

At the start, it’s always hard to know what methods will work best for something as complex as the development of disease-modifying treatments for fragile X. But, we’ve always tried to let the science lead us down the right path. At this point, the results are unequivocal, and they have shaped how we are looking ...

Fragile X syndrome reversed in adult mice

Neuron just published a new study showing that a compound that inhibits mGluR5 to correct signs of Fragile X. The work was done by a team led by Dr. Lothar Lindemann at Roche, and a group led by Dr. Mark Bear at MIT. I’ve just finished reading the new article, and I must say it ...

Research Outlook 2012

Fragile X research continues to progress at a break-neck pace, and 2012 promises to be the most important year ever. Indeed, we anticipate a watershed year: no matter how things turn out, we are sure that the landscape will be very different by the end of the year. As everyone is surely aware, three different ...