Discovering Effective Treatments & A Cure for Fragile X Syndrome
Your support enables FRAXA Research Foundation to fund groundbreaking research and life-changing clinical trials.
How Does FRAXA Help?
FRAXA’s mission is to find effective treatments and ultimately a cure for Fragile X syndrome. We directly fund research grants and fellowships at top universities around the world. We partner with biomedical and pharmaceutical companies, large and small, to bridge the gap between research discoveries and actual treatments.
Every member of our staff and Board of Directors is a parent of one or more children with Fragile X, making our commitment to this cause deeply personal.
Treatments for Fragile X are likely to help people affected by autism, Alzheimer’s, and other brain disorders.
What is Fragile X Syndrome?
Fragile X syndrome (FXS) is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4,000 boys and 1 in 8,000 girls worldwide.
Fragile X syndrome occurs when a single gene on the X chromosome shuts down. This gene makes a protein needed for normal brain development. In FXS it does not work properly, the protein is not made, and the brain does not develop as it should.
Symptoms of Fragile X syndrome can include developmental delays, social anxiety, and learning disabilities, which vary between individuals.
The Latest from FRAXA
Exploring the Auditory System Therapeutic Target for Fragile X Syndrome
Auditory system therapeutic target for Fragile X syndrome research uses a rat model to connect excess protein synthesis with disrupted circuits and auditory hypersensitivity.
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Identifying New Therapeutic Approaches Using a Human Fragile X Model
Human Fragile X syndrome model research identifies new therapeutic approaches by revealing how FMRP loss affects human neurons and brain circuits.
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Cell Type-Specific Protein Dysregulation in Fragile X Syndrome Brain Organoids
Study finds that brain cell types respond differently to gene silencing, pointing to the need for customized treatment approaches in Fragile X.
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FRAXA's Impact to Date
$38.2M
Direct Investment in Fragile X Research
49
Teams Actively Researching Fragile X Syndrome
34
Pharmaceutical and Biomedical Partners
659
Fragile X Research Grants Awarded