Each year, FRAXA funds a diverse portfolio of research. Our FRAXA Fellowships are seed funding for the future, the feedstock for the Fragile X treatment development pathway. While we are looking to promote as many promising new approaches as possible, prominent themes emerge each year, as scientists around the world tackle previously neglected areas.
Key Themes for 2021 FRAXA-Funded Fragile X Research
We are excited about the power and potential of these new projects. They are driven by some of the most innovative and dedicated scientists worldwide, powered by new technologies (organoids, CRISPR, and AI, to name a few).
We look forward eagerly to the results of these grants and to funding even more exciting projects during 2022.
2021 FRAXA-Funded Fragile X Research Grants
An Exploratory Single Blind Study of Ergoloid Mesylates, 5-Hydroxytryptophan, and the Combination in Adult Males with Fragile X Syndrome
Researchers
Elizabeth Berry-Kravis, MD, PhD
Organization
Rush University Medical Center, Chicago
Amount
106,600
Cannabinoids as a Treatment for Fragile X Syndrome
Researchers
Devin Binder, MD, PhD
Patricia Salgado Pirbhoy, PhD
Organization
University of California, Riverside
Amount
$45,000
Researchers
Antonella Borreca, PhD
Zaira Boussadia, PhD
Organization
CNR – Institute of Neuroscience
Amount
$45,000
Researchers
Artuela Çaku, MD
Armita Abolghasemi, PhD
Organization
Université de Sherbrooke
Amount
$45,000
Researchers
Brian Christie, PhD
Marie-Eve Tremblay
Organization
University of Victoria
Amount
$40,000
Researchers
Nicola Allen, PhD
James Deng
Organization
Salk Institute for Biological Studies
Amount
$45,000
Characterization of a Novel CYFIP1 – Derived Peptidomimetic Restoring the Dysregulated mRNAs Translation: Toward An Innovative Therapeutic Strategy for FXS
Researchers
Daniele Di Marino, PhD
Alice Romagnoli, PhD
Organization
Polytechnic University of Marche
Amount
$45,000
Researchers
Ilse Gantois, PhD
Nahum Sonenberg, PhD
Organization
McGill University
Amount
$45,000
Researchers
Kimberly F Raab-Graham, PhD
Chelcie F Heaney, PhD
Organization
Wake Forest School of Medicine
Amount
$45,000
Researchers
Lynne Maquat, PhD
Tatsuaki Kurosaki, PhD
Organization
University of Rochester
Amount
$45,000
Researchers
Stéphane Martin, PhD
Marie Pronto
Organization
Institut de Pharmacologie Moléculaire et Cellulaire
Amount
$45,000
Researchers
Joel Richter, PhD
Sneha Shah, PhD
Organization
University of Massachusetts Medical School
Amount
$81,401
Researcher
Elizabeth Berry-Kravis, MD, PhD
Organization
University of Massachusetts Medical School
Amount
$12,024
Researchers
Xinyu Zhao, PhD
Carissa Sirois, PhD
Organization
University of Wisconsin-Madison
Amount
$45,000
Researchers
Cara Westmark, PhD
Alejandra Gutierrez
Organization
University of Wisconsin-Madison
Amount
$45,000
Contribution of Astrocytes to Beneficial Responses of Lovastatin in Fragile X Syndrome
Researcher
Maija Castrén, MD, PhD
Organization
University of Helsinki
Amount
$8,000
Researcher
Iryna Ethell, PhD
Organization
University of California, Riverside
Amount
$35,000
FMR1 silencing and stability during human brain development; from early stage of pluripotency to 3D cortical organoids of FXS patients
Researchers
Nicola Elvasorre
Organization
University of Padova
Amount
$45,000
