trinucleotide repeat region

FRAXA Research Foundation
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Fragile X syndrome (FXS) is caused by expansion of CGG trinucleotide repeats in the FMR1 gene. The Fragile X “full mutation” – a very long expansion resulting in over 200 CGG repeats – causes silencing of the FMR1 gene.

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    FRAXA Research Foundation is dedicated to funding breakthrough research, providing $240,000 to reactivate the FMR1 gene to combat Fragile X Syndrome, with the goal of restoring vital protein function and advancing towards a cure.
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