miRNA Archives

Role of the Cerebellum in the Dysfunction of Fragile X Syndrome

FRAXA Research Foundation February 26, 2009February 23, 2024

Drs. Oostra, Warren, and Nelson discovered the Fragile X gene and its FRAXA mutation in 1991.

Correcting Fragile X Syndrome Deficits by Targeting Neonatal PKCε Signaling in the Brain Ben A. Oostra, PhD Principal Investigator Erasmus University Rotterdam, The Netherlands 2004-2005 Grant Funding: $119,000 Summary The Dutch-Belgian Fragile X Consortium led by Dr. Oostra created the

Genome-wide Epigenetic Markers in Fragile X

FRAXA Research Foundation February 5, 2009January 16, 2019

With $45,000 in grants from FRAXA Research Foundation over several years, Dr. Miklos Toth of Cornell University studied epigenetics (ie factors other than the gene itself) which can determine symptom severity in Fragile X.

Role of MicroRNAs in Fragile X Syndrome

FRAXA Research Foundation February 22, 2005March 21, 2019

Thomas Tuschl, PhD, at Rockefeller University, FRAXA research grant

With a $70,000 grant from FRAXA Research Foundation from 2004-2005, Drs. Thomas Tuschl and Neil Renwick and their team at Rockefeller University researched how FMRP interacts with miRNA in order to determine more effective treatment targets for Fragile X syndrome.